Disturbed Clockwork Resetting in Sharp-1 and Sharp-2 Single and Double Mutant Mice
نویسندگان
چکیده
منابع مشابه
Disturbed Clockwork Resetting in Sharp-1 and Sharp-2 Single and Double Mutant Mice
BACKGROUND The circadian system provides the basis to anticipate and cope with daily recurrent challenges to maintain the organisms' homeostasis. De-synchronization of circadian feedback oscillators in humans causes 'jet lag', likely contributes to sleep-, psychiatric-, metabolic disorders and even cancer. However, the molecular mechanisms leading to the disintegration of tissue-specific clocks...
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ژورنال
عنوان ژورنال: PLoS ONE
سال: 2008
ISSN: 1932-6203
DOI: 10.1371/journal.pone.0002762